Timothy J. Nelson, M.D., Ph.D., is a general internal medicine practitioner, with a specialty interest in regenerative medicine. Areas of expertise include: Congenital and degenerative heart disease, including hypoplastic left heart syndrome (HLHS), clinical trials for regenerative medicine and stem cell therapies, translational transplant medicine, application of stem cell technologies in treating degenerative diseases, and ethics of stem cell technologies and therapies. In addition to his clinical activities, Dr. Nelson is active in research and education, mentoring students and fellows, and teaching multiple courses to graduate and medical students. Dr. Nelson is the director of the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome at Mayo Clinic, Rochester, Minnesota.
Title of Abstract
Dr. Timothy Nelson is director of the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS), a research program supporting a rare congenital heart disease. The goal of the research program is to delay or prevent heart failure for individuals with HLHS. The specialized team is addressing the various aspects of these defects by using research and clinical strategies ranging from basic science to diagnostic imaging to regenerative therapies. Included in the research are two clinical trials using regenerative medicine. The first clinical trial uses stem cells derived from a baby’s own umbilical cord blood while the second clinical trial uses stem cells derived from an individual’s own bone marrow. In 2017, the program created a national HLHS consortium that allows for a decrease in the amount of time from research and discovery to the clinical application of innovative cell-based therapies. The consortium aligns regional centers to accelerate innovation for HLHS, discovery sciences, and clinical expertise by investing local resources back into research.